Uganda Covid-19 vaccine at animal testing stage, says govt scientist

Nation Media Group

What you need to know:

Dr Monica Musenero says: ...but getting the vaccine approved and all that takes time but you will be surprised- that vaccine is still going to contribute to Covid-19 fight because Covid-19 is not going to go away tomorrow.

1. Drug/vaccine discovery takes place in a laboratory by trying out molecules with theoretical effect on a disease or virus lifecycle.
2. Selected molecules are taken through other chemical tests to see if they have a chance to make it to the next levels.
3. Tests are conducted in lab animals - mice, guinea pigs, dogs and sometimes monkeys to assess safety.
4. Phase I studies – first in human studies – are conducted in humans after rigorous regulatory approval to test the safety profiles of the drug candidate. Most drug candidates fail at this stage.
5. Phase II studies are conducted in humans to assess whether the candidate vaccine actually treats the intended disease.
This comes after rigorous regulatory assessments and approval for phase I.
6. Phase III studies are conducted on thousands to hundreds of thousands of patients/humans to assess the true or near true picture of the drug candidate in real life.
7. After successful completion of phase III and thorough regulatory scrutiny and approval, the drug can then be allowed for use on the market, with requirements for pharmacovigilance, or Phase IV.
The entire process on average takes about 10 years and cost in the range of hundreds of million dollars

Uganda Covid-19 vaccine at animal testing stage, says govt scientist

What you need to know:

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